Mitochondria are responsible for producing energy within the cells. When they do not work properly, the body may not have enough energy for organs, muscles and systems to function as they should.

The prognosis varies from person to person. Mitochondrial disease can affect people very differently, depending on the organs involved, the severity of symptoms and the individual diagnosis.

Symptoms can include muscle weakness, fatigue, poor growth, seizures, learning difficulties, vision or hearing problems, heart issues, breathing difficulties and digestive problems.

Risk can depend on family history, genetic factors and symptoms. If there are concerns about mitochondrial disease, medical advice should always be sought from a qualified healthcare professional.

Yes. Mitochondrial disease can affect children and adults. Some people are diagnosed in childhood, while others may not receive a diagnosis until later in life.

It can appear at any age. For some, symptoms are present from birth or early childhood. For others, symptoms may develop gradually or appear later in life.

A person should speak to their GP or specialist consultant about their symptoms and concerns. They may then be referred for further assessment or specialist testing.

Testing decisions are made by medical professionals and depend on symptoms, medical history and clinical judgement. Concerns should be discussed with a doctor or specialist.

The NHS can provide medical advice, referrals, specialist care and information about mitochondrial disease. Speak to your GP or healthcare team for guidance.